Pow.Bio, provider for AI-enabled continuous fermentation technology, and Bühler Group, solution provider for food, feed, and advanced materials, are teaming up. The collaboration advances industrial biomanufacturing by accelerating process development, reducing unit production costs thanks to a continuous process, and improving operation performance. Bühler and Pow.Bio are now ready to begin onboarding customers.

Unlike traditional fermentation approaches that rely on batch or fed-batch processes – stop-and-start methods that require the tank to be emptied and cleaned between runs – the companies now offer an ultra-efficient and streamlined solution. The offering brings together Pow.Bio’s proprietary continuous fermentation technology with Bühler’s 165 years of engineering, delivery, installation, and commissioning services – all supported by advanced model-driven control software. The result is a platform that allows customers to establish precision fermentation capacity faster, with predictable performance, lower unit costs, and a direct path to scale.

The platform is designed for companies commercializing fermentation-derived products that are currently produced in fed-batch systems but constrained by cost, scalability, or inconsistent output. From established ingredients such as enzymes and organic acids to categories like functional proteins, specialty lipids, and bioactive compounds, the Pow.Bio-Bühler solution offers a continuous, more efficient production pathway. By replacing traditional fed-batch processes with a continuous, model-driven system, customers can achieve significantly higher productivity, improved process consistency, and more cost-effective manufacturing through an established, low-risk pathway from lab to pilot and full industrial scale.

“Our collaboration with Bühler sets a new benchmark for biomanufacturing: not just faster, but smarter and more robust,” said Shannon Hall, CEO and co-founder of Pow.Bio. “Clients can now capitalize on proven technology and global deployment expertise to unlock commercial-scale production with lower risk and unprecedented efficiency. This partnership solidifies Pow.Bio’s position at the forefront of industrial biotechnology, enabling us to deliver enduring value for our clients and the sector as a whole.”